Abstract—The present study aimed to use a method for the synthesis of some tetrahydro-dihydroxy-oxoindeno[1,2-b]pyrroles. The question this study tried to answer was this reaction can be performed without solvent and catalyst or not. To find answer to the question, Some [1,2-b]pyrroles were synthesized, via condensation of amines, alkylpropiolates, and ninhydrin at room temperature without solvent and catalyst. Therefore we have synthesized this compounds with a novel method, which is eco_friendly, cost effective, environmentally friendly, acceptive yields, solvent Free and free catalyst was developed for the synthesis of some tetrahydro-dihydroxy-oxoindeno[1,2-b]pyrroles.
Index Terms—Tetrahydro-dihydroxy-oxoindeno[1,2-b] pyrroles, free solvent, environmentally friendly, room temperature
The Authors are with the Department of Chemistry, Faculty of Science, Islamic Azad University-Tonekabon Branch, Tonekabon-Iran (E-mail: f_hatamjafari@tonekaboniau.ac.ir).
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Cite: Farhad Hatamjafari, "Environmentally Friendly Solvent Free Synthesis of Some [1,2-b]Pyrrole Derivatives at Room Temperature," International Journal of Chemical Engineering and Applications vol. 3, no. 2, pp. 152-155, 2012.
